The Owls kick off their away days with a trip to Ipswich on Saturday.
With wins against Bristol City and Mansfield under the belt, Wednesday travel to Portman Road seeking a third successive win.
Ipswich: Bialkowski, Knudsen, Chambers, Smith, Berra, Maitland-Niles, Skuse, Murphy, Fraser, Sears, Douglas
Substitutes: Gerkin, McGoldrick, Pitman, Coke, Tabb, Emmanuel, Toure
Wednesday: Westwood, Hutchinson, Loovens, Matias, McGugan, Lees, Helan, Jaoa, Lopez, Hunt, Wallace
Substitutes: Wildsmith, Palmer, Semedo, Nuhiu, Lee, Sasso, Sougou