Owls goalkeeper Keiren Westwood has lost his appeal against the red card issued at Derby on Saturday.
The Wednesday shot stopper was dismissed in the late stages of the weekend clash at the iPro Stadium.
Following an appeal, the original decision has been upheld and the 30-year-old will miss tonight’s fixture with Millwall.
Westwood will be back available for selection on Saturday when the Owls host Middlesbrough.