Manuel Pellegrini says the FA Cup is important to Manchester City.
The Citizens are joint leaders of the Premier League and are in outstanding form having won ten of their last 11 games in all competitions.
City emphatically defeated the Owls earlier this season in the Capital One Cup but were knocked out in the next round by Newcastle.
Pellegrini wants Sunday’s clash with Wednesday to be the start of a long run in the world’s most famous cup competition.
He said: “It is a very important cup for us and last year we were disappointed to be eliminated at our own ground to Wigan in the quarter-finals.
“It’s been a difficult two weeks with three games each week and December has been a key month, especially when we had to play for nine points in one week.
“We’ve got those games out of the way now and have won ten of our last 11 but now we are only thinking of Sheffield Wednesday and the FA Cup.”
Pellegrini added: “This year we have been eliminated from the Capital One Cup, so that puts an even greater focus on the FA Cup and we’ll be trying to go as far as we can in this competition.
“We had a good victory over Sheffield Wednesday earlier in the season but that game will not affect this one and we expect a difficult match on Sunday.
“We still have a number of players injured but we are finding different ways to continue our good form.”