Carlos Carvalhal is set to ring the changes for the visit of Premier League Arsenal on Tuesday night.
The Owls face the Gunners in the fourth round of the Capital One Cup and Carvalhal has four players definitely out, with three more nursing knocks.
Missing will be Michael Turner, Alex Lopez, Marco Matias and Modou Sougou, while Wednesday have fitness concerns over Keiren Westwood, Sam Hutchinson and Glenn Loovens.
Goalkeeper Joe Wildsmith will definitely feature.
Carvalhal told swfc.co.uk: “We must wait on some players but we know Turner, Lopez, Matias and Sougou will not play.
“We cannot take risks with anyone. For certain, Joe Wildsmith will play. Keiren Westwood is an amazing goalkeeper as everybody knows and Joe is a very, very talented young goalkeeper.
“I have complete confidence in Joe. When he has come into the team, he has done fantastic.
“He made his international debut for the England Under-20s recently and was then called into the Under-21s and that is a sign of the progress he has made.
“So Joe will play in this game against Arsenal. This is an important game and one we want to win.
“The Championship is where we play every week and, of course, that is the priority but we want to go as far as we possibly can in the cups.
“We have a fantastic spirit at the club and I will have 100% confidence in whoever plays in this game.”