The Owls want to bounce back with a positive result at Hillsborough after the away defeat to Bristol City, while Ipswich will be looking for a win to give them hope of a late play-off push.
Wednesday: Westwood, Hunt, Loovens, Lees, Pudil, Wallace, Bannan, Lopez, Lee, Joao, Forestieri
Substitutes: Wildsmith, Sasso, Bennett, McGugan, Matias, Hooper, Nuhiu
Ipswich: Bialkowski, Chambers, Smith, Berra, Knudsen, Douglas, Bru, Foley, Feeney, Sears, McGoldrick
Substitutes: Gerken, Pitman, Digby, Kenlock, McDonnell, Dozzell, Pringle