Carlos Carvalhal was disappointed with a controversial decision as the Owls lost 2-0 to Derby at the iPro Stadium.
Wednesday were dominant in the early stages of the game and created several chances, one of which fell to Adam Reach, whose goalbound effort was cleared off the line by Rams defender Richard Keogh.
There were claims for handball against Keogh, but the referee waved away the appeals, which bemused the Owls’ players and bench.
Goals from Cyrus Christie and Alex Pearce were enough to seal all three points for the Rams in a game that could have been very different.
Carvalhal said: “It is clear to everyone that it was a handball.
“I don’t know how this decision has not been given, and the frustrating thing is that it has such a big impact on the rest of the game.
“The incident happened after six minutes when we were on top of the game and looking most likely to take the lead, but these decisions change games.
“Despite the result I am very proud of my players and the way we played.
“Derby are a good team and we still come here and play our way to try and win the game.
“We played some good football and fought very hard.
“We tried to get the equaliser after Derby went in front, but they counter attack and this leads to the free-kick and the second goal, this is football sometimes.
“The decision had the biggest impact but now all of our focus will turn to the next game on Saturday.”