The Owls travel to the Amex Stadium looking for a win against second placed Brighton, with the Seagulls hoping for a positive result to lift them above Newcastle.
Brighton: Stockdale, Goldson, Duffy, Dunk, Pocognoli, Knockaert, Stephens, Norwood, Murphy, Hemed, Murray
Substitutes: Maenpaa, Hunt, Huenemeier, Sidwell, Kayal, Skalak, March
Wednesday: Westwood, Hunt, Lees, Loovens, Pudil, Wallace, Bannan, Hutchinson, Reach, Forestieri, Winnall
Substitutes: Wildsmith, Palmer, Sasso, Jones, McManaman, Hooper, Fletcher