The Owls Under-23s begin their preparations for the new season with a trip to Worksop Town on Monday 10 July.
Neil Thompson’s side will defend their PDL2 North and National Championships in 2017/18 after scooping both titles last season.
Wednesday pipped Hull to the top of the PDL2 North in 2016/17 and went on to defeat Millwall and the Tigers to land the play-off trophy.
The fixture will take place at Sandy Lane and kick-off at 7.00pm.
Admission is £5 and under 10s are free of charge.