The Owls will play Primeira Liga side Portimonense in Portugal during their pre-season tour across Europe.
The friendly encounter will take place at the Estádio Municipal de Albufeira on Wednesday 19 July with a 7.00pm kick-off.
Wednesday played two games against Portuguese opposition last summer – Nacional and Benfica – whilst also taking on Portimonense in a training ground exercise.
Carlos Carvalhal takes his squad to Portugal on Monday 17 July and returns to Sheffield six days later.