The Owls make their final midweek trip of the season to Loftus Road looking for a third straight away win, with the Rs hoping to better their last result, a 4-0 loss to Hull City.
QPR: Smithies, Furlong, Baptiste, Robinson, Bidwell, Freeman, Scowen, Cousins, Osayi-Samuel, Smyth, Sylla
Substitutes: Ingram, Washington, Manning, Smith, Wszolek, Kakay, Eze
Wednesday: Wildsmith, Palmer, Lees, Thorniley, Pudil, Reach, Jones, Pelupessy, Forestieri, Joao, Nuhiu
Substitutes: Dawson, Rhodes, Butterfield, Matias, Boyd, Baker, Nielsen