The Owls face Derby at Hillsborough looking for a win to climb the Championship table, with the Rams hoping for three points that could see them jump into the automatic promotion places.
Wednesday: Wildsmith, Hunt, Venancio, Loovens, Pudil, Boyd, Pelupessy, Clare, Reach, Joao, Rhodes
Substitutes: Dawson, Jones, Fox, Palmer, Nuhiu, Thorniley, Stobbs
Derby: Carson, Forsyth, Keogh, Baird, Johnson, Weimann, Vydra, Nugent, Davies, Ledley, Huddlestone
Substitutes: Roos, Palmer, Anya, Lawrence, Wisdom, Pearce, Jerome