The Owls’ Under-23s went down by the odd goal in five at Huddersfield on Monday.
It was a bittersweet afternoon for Wednesday, who lost an entertaining encounter but welcomed back defender Tom Lees from injury.
Lees played an hour of the Professional Development League 2 clash alongside Freddie Nielsen and Connor O’Grady at the heart of the defence.
Huddersfield, though, raced into a 2-0 lead with strikes from Dominic Tear and Regan Booty.
Tear’s right-foot strike from distance opened the scoring before Booty doubled the advantage with a fortuitous cross cum shot that flew into the top corner.
The home side continued to dominate and Dan Wallis produced a fine reflex save to keep the Owls in the game ahead of half time.
Neil Thompson’s side re-grouped during the interval and showed a notable improvement for the second half.
Lees had the easy task of tapping into an empty net after a goalmouth scramble and that proved his last action of note as the former Leeds man made way for Ben Hughes with a valuable hour under the belt.
But the Owls’ comeback ambitions were promptly thwarted as Huddersfield restored their two-goal advantage, with substitute Oliver Dyson firing home from close range.
Wednesday were not finished, however, and benefited from an unfortunate own goal to make it 3-2 following a teasing Fraser Preston cross.
Josh Dawodu went close right at the last but the Terriers held on to take maximum points from a thrilling contest in West Yorkshire.
Wednesday: Wallis; Lees (Hughes 60), Nielsen, O'Grady, Baker, Hunt, Clarke, Waldock (Dawodu 73), West; O'Brien (Williams 83), Preston