The Owls take on Aston Villa at Hillsborough seeking a return to winning ways following the midweek reverse at Millwall.
The Villans, meanwhile, are out to turn up the heat on the top two at the summit of the Championship.
Wednesday: Wildsmith, Hunt, Venancio, Pudil, Fox, Boyd, Pelupessy, Clare, Reach, Joao, Nuhiu
Substitutes: Dawson, Loovens, Baker, Jones, Stobbs, Butterfield, Rhodes
Villa: Johnstone, Chester, Whelan, Snodgrass, Hogan, Hourihane, Onomah, Hutton, Terry, Elmohamady, Grabban
Substitutes: Bunn, Taylor, Lansbury, Jedinak, Bjarnason, Hepburn-Murphy, Davis